Liztox 100unit: Professional Guide to Reconstitution, Dilution & Storage

Liztox 100unit, manufactured by Huons in South Korea, is a sterile, vacuum-dried formulation of Clostridium botulinum toxin type A. It is presented as a white lyophilized powder in a single-use vial, intended for reconstitution with a sterile saline solution prior to professional application.

Each vial contains 100 units of the active neurotoxin complex, along with human serum albumin as an excipient and sodium chloride for tonicity. The product is manufactured under strict quality control standards, and its market presence is an important consideration for clinic owners stocking various neurotoxin brands. For information on the regulatory status of other prominent K-toxins, professionals can reference our Coretox 50 Units: A Professional's Guide to Regulatory & Mar.

Proper receipt and inspection are the first steps in maintaining the product's specified quality. Liztox is temperature-sensitive and must be shipped and stored under controlled cold-chain conditions.

Upon receiving a shipment, immediately verify the following:

• Temperature Integrity: Confirm the package was shipped in insulated containers with cold packs and that it feels cool to the touch. Transfer the vials to a designated refrigerator immediately.
• Packaging Security: Check for any signs of tampering or damage to the external box.
• Vial Inspection: Each Liztox vial is sealed with a protective cap. The rubber stopper beneath should be intact. Before reconstitution, observe the contents. A small amount of fine, white powder should be visible at the bottom of the vial. This is normal for a vacuum-dried product.
• Documentation: Ensure the lot numbers on the vial and box match your order invoice. This traceability is critical for inventory management and authenticating your supply. The principles of product verification are universal, as outlined in our guide on How to Verify Genuine VOM Volume Fillers: An Authentication .

To prepare Liztox 100unit for clinical use, assemble the following sterile materials:

• One vial of Liztox 100unit.
• Sterile, preservative-free 0.9% sodium chloride (NaCl) injection. The use of preservative-free saline is a standard practice to prevent potential deactivation of the toxin complex.
• One sterile syringe, typically 1mL or 3mL, with appropriate graduation marks for accurate measurement of the diluent.
• One 21-gauge sterile needle for drawing the saline.
• One 30-gauge (or similar) sterile needle for injecting the saline into the Liztox vial.

Reconstitution must be performed with aseptic technique to prevent contamination.

1. Prepare the Vial: Remove the plastic cap from the Liztox vial. Disinfect the rubber stopper with an alcohol swab and allow it to air dry.
2. Draw the Diluent: Using the 21-gauge needle and your chosen syringe, draw the precise amount of sterile 0.9% sodium chloride required to achieve the desired concentration. Refer to the dilution chart below.
3. Inject the Diluent: Carefully insert the needle through the center of the rubber stopper. To prevent frothing and potential denaturation of the protein, slowly inject the saline, directing the stream against the glass wall of the vial rather than directly onto the powder.
4. Mix Gently: The vacuum within the vial may pull the saline in. After injection, remove the syringe and needle. To dissolve the powder, gently swirl the vial in a circular motion. Do not shake the vial vigorously, as this can cause foaming and may compromise the product's structure.
5. Final Inspection: The reconstituted solution should be clear, colorless, and free of any particulate matter. If the solution is cloudy or contains particles, do not use it.

The final concentration of the reconstituted solution depends on the volume of saline added. The choice of dilution is determined by the licensed practitioner based on their specific technique and treatment goals. This table provides standard reference values for achieving different concentrations from a 100-unit vial.

Practitioners should be aware that different neurotoxin products may have specific handling characteristics. Sourcing a variety of options, such as Nabota 100unit or others from the main Botulinum toxin / neurotoxin catalog, allows clinics to cater to diverse professional preferences and techniques.

Correct storage is fundamental to preserving the stability of Liztox.

• Unopened Vials: Unopened vials of Liztox 100unit must be stored in a refrigerator at a temperature between 2°C and 8°C (36°F to 46°F). Do not freeze. Always check the expiration date printed on the vial and carton before use.
• Reconstituted Solution: Once reconstituted, Liztox should be used promptly. Manufacturer guidelines generally recommend storing the reconstituted solution in a refrigerator (2°C to 8°C) and using it within 24 hours. The reconstituted product must not be frozen. Any unused solution remaining after this period should be safely discarded according to local medical waste regulations.