5.0
Easy to reconstitute
Followed manufacturer protocol, no microbead clumping.
Dr. Naomi P.
Dermatologist · Tokyo, JP
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Authentic · Lot verified
Regen Biotech, Inc. · body-filler
Aesthefill Standard
For professional use only
PDLLA-based biostimulator for progressive, natural-looking volume restoration.
4.9· 20 reviews
100% Original
Lot traceable
Cold-chain
Long expiry
Wholesale price · net professional
$217.00$303.80Save 28%
per unit · free shipping · cold-chain included
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4 more items to enable checkoutMOQ 5
Variant2 options
In stock · ships within 24hDHL Express·🇺🇸 United States
Estimated deliveryTuesday Jun 30 – Wednesday Jul 1
We ship to 🇺🇸 United States regularly — current estimates may shift slightly with customs, but in our experience parcels arrive within 4–5 days of you receiving the tracking number. Many happy clinics in United States already buy from us.
100% Original
Authentic manufacturer-sourced units only.
Lot traceable
Lot # verifiable on every box & vial.
Cold-chain
2-8°C refrigerated transport, end-to-end.
Secure payment
3D-Secure encryption + escrow available.
Insured shipping
Full coverage against damage or loss.
Replacement guarantee
Compromised on arrival? Replaced free.
About
What it is.
Aesthefill is a collagen biostimulator based on Poly-D,L-lactic Acid (PDLLA), designed to correct volume loss and improve skin structure. Its patented microsphere technology promotes neocollagenesis for gradual, long-lasting results. This product is intended for deep dermal or subcutaneous administration by trained medical professionals.
What it is
Aesthefill is an injectable biostimulatory filler composed of Poly-D,L-lactic acid (PDLLA), a biocompatible and biodegradable polymer. It is supplied as a lyophilized powder requiring reconstitution prior to injection. The product is designed to address volume loss by stimulating the patient's endogenous collagen production, leading to a gradual and natural-looking restoration of facial and body contours. The PDLLA is derived from plant-based sources for high biocompatibility.
How it works
Once injected, the porous PDLLA microspheres provide a scaffold that stimulates fibroblast activity and initiates neocollagenesis. The carrier agent is gradually absorbed by the body over several weeks, while the newly synthesized collagen network builds up in its place. This process restores volume and improves dermal thickness and elasticity. The spherical structure of the PDLLA particles is engineered to facilitate a uniform cellular response and minimize inflammatory reactions.
Clinical indications
Aesthefill is indicated for correcting moderate to severe facial wrinkles and folds, such as nasolabial folds, marionette lines, and for restoring volume in hollow areas like the temples and cheeks. It is also suitable for improving skin laxity and contouring in body areas including the neck, décolletage, hands, and buttocks. Administration is typically performed in the deep dermis or subcutaneous tissue, depending on the treatment area and desired outcome.
Why clinicians choose it
Practitioners select Aesthefill for its durable and natural-appearing results, which develop progressively over several months. The PDLLA composition has a well-documented safety profile and is associated with a low incidence of nodule formation. Its versatility for treating both facial and body indications makes it a valuable asset for comprehensive aesthetic practice. The treatment is well-suited for patients seeking gradual enhancement rather than immediate volumization.
Specifications
Technical sheet.
Composition
200mg Poly-D,L-lactic Acid (PDLLA) powder
Pack contents
1 sterile vial
Onset
Visible effects from 4-8 weeks post-treatment as collagen forms.
Duration
Up to 18-24 months after a complete treatment course.
Injection depth
Deep dermis, subcutaneous layer.
Storage
Room temp 15-25°C. Keep away from direct sunlight.
Shelf life
24 months unopened
Manufacturer
Regen Biotech, Inc.
Origin
South Korea
Regulatory
KFDA certified. Manufacturer-certified · See documentation.
Authenticity & traceability
Every unit, verifiable.
- Factory-sealed packaging with manufacturer hologram
- Lot number matches across box, vial and insert
- Certificate of Authenticity (COA) included with each lot
- Optional lot verification with the laboratory
Certificate of Authenticity
Aesthefill Standard
- Manufacturer
- Regen Biotech, Inc.
- Lot No.
- DF-LOT-58291
- Expiry
- Q4-2027
- Cold chain
- ✓ Intact
- Seal status
- ✓ Sealed
Shipping & cold chain
From our fridge
to yours.
Refrigerated dispatch
2-8°C reefer packaging with verified temp-log inside.
Insured & tracked
Real-time tracking, full coverage, customs handled.
Free worldwide
Free shipping on every order. 3-7 business days.
Cold-chain commitment · if your shipment arrives compromised, photograph the temp-log on opening — we replace it free, no questions asked.
Reviews
Verified by clinicians.
4.9
20 verified reviews
5★
17
4★
3
3★
0
2★
0
1★
0
Verified
5.0
Great for jawline
Subtle PCL definition, my mid-50s patients love it.
Clinique Vermeil
Cosmetic group · Lyon, FR
5.0
Great for jawline
Subtle PCL definition, my mid-50s patients love it.
Dr. Rafael T.
Plastic Surgeon · Mexico City, MX
4.7
Solid result with Aesthefill
Aesthefill integrates beautifully, no tyndall, no nodules at follow-up. Patients describe results as 'natural'.
Dr. Marcus R.
Dermatologist · London, UK
4.9
Aesthefill vs the alternatives
Side-by-side with my previous brand on matched patients — Aesthefill held up just as well, at a better price point.
Dr. Elena V.
Dermatologist · Milan, IT
5.0
Worth the wait
Slow build, but the 'where did you get that done' result is unreal.
Vermilion Clinic
Aesthetic clinic · Brussels, BE
Frequently asked
Purchase questions.
Is this authentic?+
Yes. We source products directly from manufacturers or their authorized distributors. Each box is factory-sealed and includes a unique batch number.
What is the shelf life on arrival?+
We guarantee a minimum of 12 months remaining shelf life for all products shipped from our facility.
How should this be stored?+
Store unopened vials at room temperature (15-25°C) in a dry place, protected from direct sunlight.
What is the recommended treatment protocol?+
A standard protocol consists of 2-3 treatment sessions, spaced 4 to 6 weeks apart, to achieve optimal results. Clinicians must consult the manufacturer's official instructions for reconstitution and administration techniques.
Are there contraindications?+
Contraindications include active skin inflammation or infection at the treatment site, known hypersensitivity to PDLLA, and a history of keloid scarring. A thorough patient assessment is required before treatment.
Where do you ship from?+
Most shipments are dispatched from our largest warehouses in South Korea, Europe and Vietnam. We route each order from the closest hub to your destination to minimise transit time and keep the cold chain intact end-to-end.
Where is your company based?+
Discount Fillers is a United States–based company with operational presence in South Korea, Hong Kong, Europe and Vietnam — giving us direct manufacturer relationships and local cold-chain logistics across the regions where most authentic aesthetic supplies originate.
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2 min ago