5.0
Effective numbing
30min application — perfect comfort for injectables.
Dr. Priya S.
Dermatologist · Mumbai, IN
Authentic · Lot verified
Inist Bio Pharmaceutical Co., Ltd. · lidocaine-cream
J-CAIN Cream 500g
For professional use only
High-concentration topical lidocaine for effective pre-procedure cutaneous anesthesia.
4.9· 19 reviews
100% Original
Lot traceable
Cold-chain
Long expiry
Wholesale price · net professional
$82.40$115.36Save 28%
per unit · free shipping · cold-chain included
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4 more items to enable checkoutMOQ 5
In stock · ships within 24hDHL Express·🇺🇸 United States
Estimated deliveryTuesday Jun 30 – Wednesday Jul 1
We ship to 🇺🇸 United States regularly — current estimates may shift slightly with customs, but in our experience parcels arrive within 4–5 days of you receiving the tracking number. Many happy clinics in United States already buy from us.
100% Original
Authentic manufacturer-sourced units only.
Lot traceable
Lot # verifiable on every box & vial.
Cold-chain
2-8°C refrigerated transport, end-to-end.
Secure payment
3D-Secure encryption + escrow available.
Insured shipping
Full coverage against damage or loss.
Replacement guarantee
Compromised on arrival? Replaced free.
About
What it is.
J-CAIN Cream is a professional-grade topical anesthetic containing 10.56% lidocaine. Supplied in a large 500g tub, it is designed for cost-effective use in clinics to numb the skin prior to minimally invasive aesthetic procedures, reducing patient discomfort.
What it is
J-CAIN Cream is a topical anesthetic formulated with a high concentration of lidocaine (10.56%). This water-based cream is engineered for professional application on intact skin to provide temporary local anesthesia. Its large 500g packaging makes it an economical choice for medical and aesthetic practices that perform a high volume of procedures requiring pre-treatment numbing, ensuring both efficacy and cost-efficiency. It is widely used to minimize pain associated with dermal needle insertions and superficial dermatological treatments.
How it works
The active ingredient, lidocaine, is an amide-type local anesthetic. Upon topical application, it penetrates the epidermis and dermis to reach cutaneous pain receptors and nerve endings. Lidocaine works by reversibly blocking voltage-gated sodium channels within the neuronal cell membrane. This action prevents the influx of sodium ions necessary for the initiation and conduction of nerve impulses. As a result, the transmission of pain signals from the treated area is inhibited, producing a temporary numbing effect.
Clinical indications
J-CAIN Cream is indicated for providing topical anesthesia on intact skin prior to superficial dermatological procedures. Common applications include numbing for needle-based treatments such as filler injections, mesotherapy, and botulinum toxin administration. It is also suitable for use before microneedling, thread lifting, fractional laser treatments, and permanent makeup or tattoo application. Application should be confined to the specific treatment area, avoiding mucous membranes and non-intact skin.
Why clinicians choose it
Clinicians select J-CAIN Cream for its potent and reliable anesthetic properties, which enhance patient comfort and tolerance during procedures. The high 10.56% lidocaine concentration ensures a profound and rapid numbing effect. The 500g tub format presents a significant cost-per-application advantage over smaller tubes, making it ideal for busy practices. Its stable, non-oily cream base is easy to apply evenly and can be removed cleanly without leaving residue, ensuring a clear field for subsequent treatment.
Specifications
Technical sheet.
Composition
Lidocaine 10.56% (105.6mg/g)
Pack contents
500g cream in a sealed tub
Onset
20-30 minutes after application under occlusion
Duration
60-90 minutes after cream removal
Injection depth
N/A (Topical application only)
Storage
Room temperature 1-30°C. Keep sealed.
Shelf life
36 months unopened
Manufacturer
Inist Bio Pharmaceutical Co., Ltd.
Origin
South Korea
Regulatory
KFDA approved · See documentation
Authenticity & traceability
Every unit, verifiable.
- Factory-sealed packaging with manufacturer hologram
- Lot number matches across box, vial and insert
- Certificate of Authenticity (COA) included with each lot
- Optional lot verification with the laboratory
Certificate of Authenticity
J-CAIN Cream 500g
- Manufacturer
- Inist Bio Pharmaceutical Co., Ltd.
- Lot No.
- DF-LOT-58291
- Expiry
- Q4-2027
- Cold chain
- ✓ Intact
- Seal status
- ✓ Sealed
Shipping & cold chain
From our fridge
to yours.
Refrigerated dispatch
2-8°C reefer packaging with verified temp-log inside.
Insured & tracked
Real-time tracking, full coverage, customs handled.
Free worldwide
Free shipping on every order. 3-7 business days.
Cold-chain commitment · if your shipment arrives compromised, photograph the temp-log on opening — we replace it free, no questions asked.
Reviews
Verified by clinicians.
4.9
19 verified reviews
5★
15
4★
4
3★
0
2★
0
1★
0
Verified
4.3
Patients comfortable
Less anxiety in the chair. Worth every cent.
Beauté Lab
Multi-site clinic · Paris, FR
5.0
Reorder constantly
Goes through this tub fast.
Dr. Sofia H.
Aesthetic Physician · Madrid, ES
4.8
Smooth texture
Spreads easily, doesn't drip.
Dr. Ines A.
Dermatologist · Lisbon, PT
5.0
Smooth texture
Spreads easily, doesn't drip.
Dr. Ines A.
Dermatologist · Lisbon, PT
5.0
Honest review of J-CAIN Cream 500g
Used J-CAIN Cream 500g on 18 patients this month. Zero adverse events, consistent onset, photos look great.
Skin Lounge
Boutique clinic · Zurich, CH
Frequently asked
Purchase questions.
Is this authentic?+
Yes, all products are sourced directly from verified manufacturers or their authorized distributors to guarantee authenticity and quality.
What is the shelf life on arrival?+
We guarantee a minimum of 12 months remaining shelf life on all products shipped from our warehouse.
How should this be stored?+
Store the sealed tub at room temperature between 1°C and 30°C, away from direct sunlight. Do not freeze.
What is the recommended treatment protocol?+
Apply a thick, even layer of cream to intact skin. For enhanced effect, cover with an occlusive film for 20-30 minutes. Thoroughly cleanse the skin to remove all cream before starting the procedure.
Are there contraindications?+
Do not use on patients with a known hypersensitivity to lidocaine or other amide-type anesthetics. Avoid application on broken skin, eczematous areas, mucous membranes, or near the eyes.
Where do you ship from?+
Most shipments are dispatched from our largest warehouses in South Korea, Europe and Vietnam. We route each order from the closest hub to your destination to minimise transit time and keep the cold chain intact end-to-end.
Where is your company based?+
Discount Fillers is a United States–based company with operational presence in South Korea, Hong Kong, Europe and Vietnam — giving us direct manufacturer relationships and local cold-chain logistics across the regions where most authentic aesthetic supplies originate.
J-CAIN Cream 500g
$82.40 · 1 unit
✓
Verified purchase
Dr. Sofia H. · Madrid
Bought 5 × J-CAIN Cream 500g
2 min ago