5.0
Reliable supply
Cold-chain shipping perfect every time.
Dr. Ines A.
Dermatologist · Lisbon, PT
Authentic · Lot verified
Daehan New Pharm · etc
Liporase
For professional use only
A purified enzyme solution for the targeted dissolution of hyaluronic acid fillers.
4.9· 14 reviews
100% Original
Lot traceable
Cold-chain
Long expiry
Wholesale price · net professional
$82.00$114.80Save 28%
per unit · free shipping · cold-chain included
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4 more items to enable checkoutMOQ 5
In stock · ships within 24hDHL Express·🇺🇸 United States
Estimated deliveryTuesday Jun 30 – Wednesday Jul 1
We ship to 🇺🇸 United States regularly — current estimates may shift slightly with customs, but in our experience parcels arrive within 4–5 days of you receiving the tracking number. Many happy clinics in United States already buy from us.
100% Original
Authentic manufacturer-sourced units only.
Lot traceable
Lot # verifiable on every box & vial.
Cold-chain
2-8°C refrigerated transport, end-to-end.
Secure payment
3D-Secure encryption + escrow available.
Insured shipping
Full coverage against damage or loss.
Replacement guarantee
Compromised on arrival? Replaced free.
About
What it is.
Liporase is a sterile, lyophilized hyaluronidase preparation for correcting or managing hyaluronic acid (HA) filler treatments. It enzymatically depolymerizes HA gel, facilitating its rapid clearance. This product is an essential tool for aesthetic practitioners for both elective corrections and emergency vascular management.
What it is
Liporase is a brand of hyaluronidase, a tissue-spreading enzyme used in aesthetic medicine. It is supplied as a sterile, white, lyophilized powder in glass vials, designed for reconstitution with a suitable sterile solvent like saline solution. Its primary function is to break down hyaluronic acid, making it an indispensable corrective agent for clinicians working with HA-based dermal fillers and a critical component of emergency protocols.
How it works
The active ingredient, hyaluronidase, acts as a catalyst for the hydrolysis of hyaluronic acid. It specifically cleaves the β-1,4-glycosidic linkages between N-acetylglucosamine and glucuronic acid residues in the HA polymer chain. This process rapidly reduces the viscosity of the HA gel, breaking it down into smaller, soluble oligosaccharides. These fragments are then naturally absorbed and metabolized by the body, effectively reversing the filler's volumizing effect.
Clinical indications
Liporase is indicated for the enzymatic dissolution of hyaluronic acid-based dermal fillers. It is used to address undesirable outcomes such as overcorrection, asymmetry, lumpiness, nodules, or the Tyndall effect. Furthermore, it is a critical first-line treatment for the emergency management of vascular compromise or impending necrosis resulting from the accidental intravascular injection of an HA filler. It should be injected directly into the affected subcutaneous or dermal tissue.
Why clinicians choose it
Clinicians rely on Liporase for its consistent potency and rapid onset of action, making it a dependable tool for managing HA filler treatments. The freeze-dried powder format ensures product stability and a long shelf life. Its established use in the field provides a high degree of predictability for both routine corrections and critical safety interventions, enhancing patient safety and allowing for greater control over aesthetic outcomes.
Specifications
Technical sheet.
Composition
Hyaluronidase 1,500 I.U.
Pack contents
10 vials x 1,500 I.U. per box
Onset
Visible results may occur within 24-48 hours.
Duration
Enzymatic action is immediate; dissolved HA does not reconstitute.
Injection depth
Subcutaneous tissue; into the site of filler deposition.
Storage
Store unopened vials in a refrigerator (2-8°C). Protect from light.
Shelf life
36 months unopened
Manufacturer
Daehan New Pharm Co., Ltd.
Origin
South Korea
Regulatory
KFDA approved · Manufacturer-certified · See documentation
Authenticity & traceability
Every unit, verifiable.
- Factory-sealed packaging with manufacturer hologram
- Lot number matches across box, vial and insert
- Certificate of Authenticity (COA) included with each lot
- Optional lot verification with the laboratory
Certificate of Authenticity
Liporase
- Manufacturer
- Daehan New Pharm
- Lot No.
- DF-LOT-58291
- Expiry
- Q4-2027
- Cold chain
- ✓ Intact
- Seal status
- ✓ Sealed
Shipping & cold chain
From our fridge
to yours.
Refrigerated dispatch
2-8°C reefer packaging with verified temp-log inside.
Insured & tracked
Real-time tracking, full coverage, customs handled.
Free worldwide
Free shipping on every order. 3-7 business days.
Cold-chain commitment · if your shipment arrives compromised, photograph the temp-log on opening — we replace it free, no questions asked.
Reviews
Verified by clinicians.
4.9
14 verified reviews
5★
12
4★
2
3★
0
2★
0
1★
0
Verified
4.7
Liporase vs the alternatives
Side-by-side with my previous brand on matched patients — Liporase held up just as well, at a better price point.
Dr. Priya S.
Dermatologist · Mumbai, IN
4.8
Lifesaver
Hyaluronidase resolved a nodule in 24h. Calm in the room.
Dr. Rafael T.
Plastic Surgeon · Mexico City, MX
5.0
Always have on hand
Emergency stock — never know when you'll need it.
Aesthetica Roma
Clinic group · Rome, IT
5.0
Pharmacy-grade
Certificate matched, lot looks pristine.
Dr. Carlos M.
Aesthetic Physician · Barcelona, ES
5.0
Reliable supply
Cold-chain shipping perfect every time.
Skin Lab MX
Cosmetic clinic · Monterrey, MX
Frequently asked
Purchase questions.
Is this authentic?+
We source all products directly from the manufacturer or their authorized distributors to ensure authenticity and supply chain integrity.
What is the shelf life on arrival?+
Products are dispatched with a minimum of 12 months shelf life remaining, though the actual expiry date is typically much longer.
How should this be stored?+
Unopened vials must be stored in a refrigerator between 2-8°C (35.6-46.4°F). Once reconstituted, immediate use is recommended.
What is the recommended treatment protocol?+
Protocols vary by clinical scenario. The lyophilized powder must be reconstituted, typically with 1-5ml of bacteriostatic saline, before use. Refer to established clinical guidelines for specific dilution and injection techniques.
Are there contraindications?+
Contraindications include known hypersensitivity to hyaluronidase. A skin patch test is often recommended prior to full treatment to assess for potential allergic reactions.
Where do you ship from?+
Most shipments are dispatched from our largest warehouses in South Korea, Europe and Vietnam. We route each order from the closest hub to your destination to minimise transit time and keep the cold chain intact end-to-end.
Where is your company based?+
Discount Fillers is a United States–based company with operational presence in South Korea, Hong Kong, Europe and Vietnam — giving us direct manufacturer relationships and local cold-chain logistics across the regions where most authentic aesthetic supplies originate.
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2 min ago