5.0
Smooth onset 👌
Onset around day 3, full effect by day 10. Patients noticed barely any droop. Reordering.
Dr. Elena V.
Dermatologist · Milan, IT
Authentic · Lot verified
Hugel · botox
Bienox 100 units
For professional use only
A high-purity neurotoxin for precise and predictable aesthetic outcomes.
4.9· 17 reviews
100% Original
Lot traceable
Cold-chain
Long expiry
Wholesale price · net professional
$72.20$101.08Save 28%
per unit · free shipping · cold-chain included
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4 more items to enable checkoutMOQ 5
Variant2 options
In stock · ships within 24hDHL Express·🇺🇸 United States
Estimated deliveryTuesday Jun 30 – Wednesday Jul 1
We ship to 🇺🇸 United States regularly — current estimates may shift slightly with customs, but in our experience parcels arrive within 4–5 days of you receiving the tracking number. Many happy clinics in United States already buy from us.
100% Original
Authentic manufacturer-sourced units only.
Lot traceable
Lot # verifiable on every box & vial.
Cold-chain
2-8°C refrigerated transport, end-to-end.
Secure payment
3D-Secure encryption + escrow available.
Insured shipping
Full coverage against damage or loss.
Replacement guarantee
Compromised on arrival? Replaced free.
About
What it is.
Bienox 100unit is a sterile, purified clostridium botulinum toxin type A complex for intramuscular injection. It is indicated for the temporary improvement of moderate to severe dynamic rhytids, offering practitioners a reliable formulation for achieving consistent results in facial aesthetics.
What it is
Bienox 100unit is a sterile, vacuum-dried formulation of purified botulinum toxin type A, derived from the fermentation of Clostridium botulinum. Each vial contains 100 units of the neurotoxin complex, alongside human serum albumin as a stabilizer and sodium chloride as a tonicity agent. It is presented as a fine white powder intended for reconstitution with sterile, preservative-free 0.9% sodium chloride solution prior to clinical use for aesthetic chemodenervation.
How it works
Upon intramuscular injection, Bienox blocks the presynaptic release of acetylcholine at the neuromuscular junction. This inhibition of the neurotransmitter prevents the target muscle from contracting. The resulting temporary and localized muscle relaxation leads to a reduction in the appearance of overlying dynamic wrinkles, such as glabellar lines or crow's feet. The clinical effect is reversible as the nerve terminals gradually recover function over several months.
Clinical indications
Bienox 100unit is indicated for the temporary improvement in the appearance of moderate to severe dynamic facial lines in adults. Primary treatment areas include glabellar lines, horizontal forehead lines, and lateral canthal lines (crow's feet). Administration is performed via intramuscular injection into the specific muscles responsible for creating these rhytids, such as the corrugator, procerus, frontalis, or orbicularis oculi muscles. Dosage and injection pattern are tailored to individual patient anatomy.
Why clinicians choose it
Clinicians may choose Bienox for its high-purity formulation and manufacturing consistency, which supports predictable clinical outcomes. Produced by Hugel Inc., a leading South Korean biopharmaceutical manufacturer, this product offers a performance profile comparable to other globally recognized botulinum toxin brands. The 100-unit vial provides dosing flexibility for treating multiple facial zones or for tailored treatments based on patient muscle mass and desired aesthetic goals.
Specifications
Technical sheet.
Composition
Clostridium Botulinum Toxin Type A (100 units), Human Serum Albumin (0.5mg), Sodium Chloride (0.9mg)
Pack contents
1 vial
Onset
Typically 3-7 days
Duration
Approximately 3-4 months
Injection depth
Intramuscular (IM)
Storage
2-8°C refrigerated
Shelf life
36 months from date of manufacture (unopened)
Manufacturer
Hugel Inc.
Origin
South Korea
Regulatory
KFDA approved. Regulatory status may vary by jurisdiction.
Authenticity & traceability
Every unit, verifiable.
- Factory-sealed packaging with manufacturer hologram
- Lot number matches across box, vial and insert
- Certificate of Authenticity (COA) included with each lot
- Optional lot verification with the laboratory
Certificate of Authenticity
Bienox 100 units
- Manufacturer
- Hugel
- Lot No.
- DF-LOT-58291
- Expiry
- Q4-2027
- Cold chain
- ✓ Intact
- Seal status
- ✓ Sealed
Shipping & cold chain
From our fridge
to yours.
Refrigerated dispatch
2-8°C reefer packaging with verified temp-log inside.
Insured & tracked
Real-time tracking, full coverage, customs handled.
Free worldwide
Free shipping on every order. 3-7 business days.
Cold-chain commitment · if your shipment arrives compromised, photograph the temp-log on opening — we replace it free, no questions asked.
Reviews
Verified by clinicians.
4.9
17 verified reviews
5★
15
4★
2
3★
0
2★
0
1★
0
Verified
5.0
Eyebrow lift looks natural
Subtle 2mm lift, exactly the kind of result that gets referrals.
Clinique Vermeil
Cosmetic group · Lyon, FR
4.8
Glabella win
Patient was a 'permanent frown' — gone at day 7.
Dr. Marcus R.
Dermatologist · London, UK
4.9
Will reorder
Lot certificate clean, shipping was cold. No complaints.
Dr. Felix W.
Aesthetic Physician · Vienna, AT
4.4
Eyebrow lift looks natural
Subtle 2mm lift, exactly the kind of result that gets referrals.
Aesthetica Roma
Clinic group · Rome, IT
5.0
Great unit economy
Better cost-per-unit than what I was using. Same clinical result.
Dr. Ines A.
Dermatologist · Lisbon, PT
Frequently asked
Purchase questions.
Is this authentic?+
Yes, we source all products directly from the manufacturer or their authorized distributors to guarantee authenticity.
What is the shelf life on arrival?+
Products are shipped with a minimum of 12 months of shelf life remaining, ensuring sufficient time for clinical use.
How should this be stored?+
Unopened vials must be stored in a refrigerator at 2-8°C. After reconstitution, it should be used promptly as per manufacturer guidance.
What is the recommended treatment protocol?+
Reconstitution, dilution, and dosage are determined by the treating medical professional based on patient assessment and the area being treated.
Are there contraindications?+
Contraindications include known hypersensitivity to any component, infection at the proposed injection site, and patients with neuromuscular junction disorders.
Where do you ship from?+
Most shipments are dispatched from our largest warehouses in South Korea, Europe and Vietnam. We route each order from the closest hub to your destination to minimise transit time and keep the cold chain intact end-to-end.
Where is your company based?+
Discount Fillers is a United States–based company with operational presence in South Korea, Hong Kong, Europe and Vietnam — giving us direct manufacturer relationships and local cold-chain logistics across the regions where most authentic aesthetic supplies originate.
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