5.0
Rejuran Tone-Up Booster delivered
Rejuran Tone-Up Booster performed exactly as expected — clean lot, predictable result, patients happy. Reordering this week.
Vermilion Clinic
Aesthetic clinic · Brussels, BE
Authentic · Lot verified
Pharma Research · skin-booster
Rejuran Tone-Up Booster
For professional use only
A dual-action skin booster for dermal regeneration and targeted depigmentation.
4.8· 19 reviews
100% Original
Lot traceable
Cold-chain
Long expiry
Wholesale price · net professional
$197.00$275.80Save 28%
per unit · free shipping · cold-chain included
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4 more items to enable checkoutMOQ 5
Variant7 options
In stock · ships within 24hDHL Express·🇺🇸 United States
Estimated deliveryTuesday Jun 30 – Wednesday Jul 1
We ship to 🇺🇸 United States regularly — current estimates may shift slightly with customs, but in our experience parcels arrive within 4–5 days of you receiving the tracking number. Many happy clinics in United States already buy from us.
100% Original
Authentic manufacturer-sourced units only.
Lot traceable
Lot # verifiable on every box & vial.
Cold-chain
2-8°C refrigerated transport, end-to-end.
Secure payment
3D-Secure encryption + escrow available.
Insured shipping
Full coverage against damage or loss.
Replacement guarantee
Compromised on arrival? Replaced free.
About
What it is.
Rejuran Tone-Up Booster is a professional-grade mesotherapy solution combining Polynucleotide (PN) for skin repair with key depigmenting agents. Its dual-vial system is formulated to improve overall skin quality while addressing uneven skin tone, dullness, and hyperpigmentation for a brighter, more luminous complexion.
What it is
Rejuran Tone-Up Booster is a two-component biostimulatory solution designed for professional aesthetic use. It consists of a primary vial containing salmon-derived polynucleotide (c-PDRN) and hyaluronic acid for dermal hydration and repair, and a secondary vial with a powder of ascorbic acid, glutathione, and tranexamic acid. When combined, these components work synergistically to regenerate tissue and correct pigmentation irregularities, enhancing skin radiance and clarity.
How it works
The mechanism of action is multi-faceted. The Polynucleotide (PN) in Vial 1 acts as a biostimulator, binding to fibroblast receptors to promote the synthesis of collagen, elastin, and extracellular matrix components, thereby improving skin density and elasticity. The active ingredients in Vial 2—glutathione, ascorbic acid, and tranexamic acid—collectively inhibit tyrosinase activity and melanin synthesis, reduce oxidative stress, and interrupt inflammatory pathways associated with hyperpigmentation.
Clinical indications
This product is indicated for the treatment of dull, lackluster skin, uneven skin tone, solar lentigines, and post-inflammatory hyperpigmentation (PIH). It is administered into the superficial dermis using mesotherapy techniques, such as micro-papular injections or via microneedling devices. Suitable treatment areas include the full face, neck, and décolletage where signs of photoaging and pigmentation are present. A course of multiple sessions is typically recommended for optimal outcomes.
Why clinicians choose it
Clinicians select Rejuran Tone-Up Booster for its comprehensive, dual-approach to skin rejuvenation. It is well-suited for patients who require both structural skin improvement and targeted action against pigmentation. The two-vial system ensures the stability and potency of the active ingredients, particularly the volatile ascorbic acid, until the point of application. This formulation provides a reliable method for addressing complex concerns of aging and dyschromia within a single treatment protocol.
Specifications
Technical sheet.
Composition
Vial I: Polynucleotide (PN), Hyaluronic Acid (HA). Vial II: Ascorbic Acid, Glutathione, Tranexamic Acid.
Pack contents
3 sets, each containing 1 x Vial I (3ml Liquid) + 1 x Vial II (0.1g Powder)
Onset
Initial improvements may be visible after 7-10 days; cumulative results after a full course.
Duration
Results are maintained with periodic follow-up treatments, typically every 6 months.
Injection depth
Superficial dermis
Storage
Room temp 1-30°C. Protect from direct sunlight.
Shelf life
36 months unopened
Manufacturer
Pharma Research Co., Ltd.
Origin
South Korea
Regulatory
KFDA approved · Manufacturer-certified. See documentation.
Authenticity & traceability
Every unit, verifiable.
- Factory-sealed packaging with manufacturer hologram
- Lot number matches across box, vial and insert
- Certificate of Authenticity (COA) included with each lot
- Optional lot verification with the laboratory
Certificate of Authenticity
Rejuran Tone-Up Booster
- Manufacturer
- Pharma Research
- Lot No.
- DF-LOT-58291
- Expiry
- Q4-2027
- Cold chain
- ✓ Intact
- Seal status
- ✓ Sealed
Shipping & cold chain
From our fridge
to yours.
Refrigerated dispatch
2-8°C reefer packaging with verified temp-log inside.
Insured & tracked
Real-time tracking, full coverage, customs handled.
Free worldwide
Free shipping on every order. 3-7 business days.
Cold-chain commitment · if your shipment arrives compromised, photograph the temp-log on opening — we replace it free, no questions asked.
Reviews
Verified by clinicians.
4.8
19 verified reviews
5★
15
4★
4
3★
0
2★
0
1★
0
Verified
4.8
Best skin product 2026
Honest take — best skin booster I've worked with.
Dr. Theo V.
Plastic Surgeon · Athens, GR
5.0
Best skin product 2026
Honest take — best skin booster I've worked with.
Dr. Ines A.
Dermatologist · Lisbon, PT
4.8
Rejuran Tone-Up Booster is the real deal
I was skeptical at first. After 6 weeks of using Rejuran Tone-Up Booster in the clinic, I'm a convert. Recommending to colleagues.
Beauté Lab
Multi-site clinic · Paris, FR
5.0
Selling itself
Posted result on Instagram, three new bookings the same day.
Aesthetica Roma
Clinic group · Rome, IT
4.4
Great for décolleté
Hands and chest treatments — gorgeous results.
Dr. Yuki F.
Dermatologist · Seoul, KR
Frequently asked
Purchase questions.
Is this authentic?+
All products are sourced directly from the manufacturer or their authorized distributors to ensure authenticity.
What is the shelf life on arrival?+
We guarantee a minimum of 12 months remaining shelf life on all products shipped to our clinical partners.
How should this be stored?+
Store at room temperature between 1-30°C, away from direct sunlight and freezing conditions.
What is the recommended treatment protocol?+
A standard protocol consists of 3-4 sessions spaced 3-4 weeks apart, followed by maintenance sessions every 6 months as needed.
Are there contraindications?+
This product is contraindicated for patients with a known hypersensitivity to any of its components, active skin infections at the treatment site, or autoimmune diseases.
Where do you ship from?+
Most shipments are dispatched from our largest warehouses in South Korea, Europe and Vietnam. We route each order from the closest hub to your destination to minimise transit time and keep the cold chain intact end-to-end.
Where is your company based?+
Discount Fillers is a United States–based company with operational presence in South Korea, Hong Kong, Europe and Vietnam — giving us direct manufacturer relationships and local cold-chain logistics across the regions where most authentic aesthetic supplies originate.
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2 min ago